Qualifications
- Ph.D. in Chemistry with a focus on synthetic organic chemistry.
- 15+ years of experience in small molecule drug discovery experience in an industrial biotechnology or pharmaceutical setting.
- Comprehensive medicinal chemistry knowledge from hits to clinical candidate selection.
- Proven track record of success in advancing programs from leads to advanced candidates.
- Extensive experience with lead compound optimization in the areas of potency, selectivity, solubility, ADME and PK.
- Conceptual understanding of cell-based and MS-based profiling assays.
- Able to objectively evaluate the results to advance compound optimization.
- Experience with all current medicinal chemistry instrumentation: HPLC, LC-MS, NMR crystallography, and purification systems.
- Expert in using common medicinal chemistry software: electronic notebook; structure drawing; data spreadsheet analysis; data visualization; structure viewing; literature, chemical and database searching.
- Committed to staying current with the latest scientific breakthroughs in the medicinal chemistry field through continued reading of the literature and attendance of scientific conferences.
- A team player with experience communicating with a multidisciplinary team, and experience managing a team of chemists. Accountable for the medicinal chemistry activities and progress of the company. Highly organized with excellent analytical, strategy, documentation, time management, and multi-tasking skills.
- Demonstrated success in the design, medicinal chemical optimization, and formulation/delivery of small molecule therapeutics.
- Demonstrable experience with successful IND submissions or equivalent is preferred.
- Experience in venture-backed companies is strongly preferred.
- Outstanding scientific leadership, collaboration, and management skills with an integrated view of business and scientific issues.
- Excellent verbal and written communication skills.
- Ability to interact with staff (at all levels) productively in a fast-paced environment.
- High degree of energy, attention to detail, and a passion for delivering important new therapies to patients with devastating diseases.
Expected Salary Range: $260,000-$290,000 (Compensation and leveling will be commensurate with experience and expertise and could fall outside of the stated range)
In Addition To Competitive Salaries, Vicinitas Offer The Following
- Early-stage Equity
- Four Medical Plan Options
- Short Term and Long-Term Disability
- Group Term Life Insurance
- FSA Plans (medical, dependent daycare and commuter accounts)
- 401k Plan
- Generous Annual Holiday Schedule
- Unlimited Flexible Time Off
- Annual Year-end Shut Down